All-trans-retinoic acid and valproic acid: A combinatorial approach for the treatment of nephrotic syndrome

Massive proteinuria, oedema, hypoalbuminemia, and hyperlipidemia are the hallmarks of nephrotic syndrome (NS). Recently, epigenetic pathways in renal diseases have been identified. The present work hypothesizes using the combination of two epigenetic drugs all-trans retinoic acid (ATRA) and valproic...

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Bibliographic Details
Main Authors: Rini Varghese, Anuradha Majumdar
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Current Research in Biotechnology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590262824000078