Identification of targets of miR-200b by a SILAC-based quantitative proteomic approach

Identification of targets of miR-200b by a SILAC-based quantitative proteomic approach

miRNAs regulate gene expression by binding to cognate mRNAs causing mRNA degradation or translational repression. Mass spectrometry-based proteomic analysis is being widely used to identify miRNA targets. The miR-200b miRNA cluster is often overexpressed in multiple cancer types, but the identity of...

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Bibliographic Details
Main Authors: Arivusudar Marimuthu, Tai-Chung Huang, Lakshmi Dhevi N. Selvan, Santosh Renuse, Raja Sekhar Nirujogi, Praveen Kumar, Sneha M. Pinto, Sudha Rajagopalan, Akhilesh Pandey, H.C. Harsha, Aditi Chatterjee
Format: Article
Language:English
Published: Elsevier 2014-09-01
Series:EuPA Open Proteomics
Subjects:
Mass spectrometry
miRNA targets
HT-1080
Online Access:http://www.sciencedirect.com/science/article/pii/S2212968514000312

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http://www.sciencedirect.com/science/article/pii/S2212968514000312

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