A modular approach to catalytic stereoselective synthesis of chiral 1,2-diols and 1,3-diols

Abstract Optically pure 1,2-diols and 1,3-diols are the most privileged structural motifs, widely present in natural products, pharmaceuticals and chiral auxiliaries or ligands. However, their synthesis relies on the use of toxic or expensive metal catalysts or suffer from low regioselectivity. Cata...

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Bibliographic Details
Main Authors: Sheng Xu, Yuanyuan Ping, Yinyan Su, Haoyun Guo, Aowei Luo, Wangqing Kong
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-55744-3