Metabolic modeling-based drug repurposing in Glioblastoma

Abstract The manifestation of intra- and inter-tumor heterogeneity hinders the development of ubiquitous cancer treatments, thus requiring a tailored therapy for each cancer type. Specifically, the reprogramming of cellular metabolism has been identified as a source of potential drug targets. Drug d...

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Bibliographic Details
Main Authors: Claudio Tomi-Andrino, Alina Pandele, Klaus Winzer, John King, Ruman Rahman, Dong-Hyun Kim
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-14721-w