Caspase-1 is involved in the genesis of inflammatory hypernociception by contributing to peripheral IL-1β maturation

<p>Abstract</p> <p>Background</p> <p>Caspase-1 is a cysteine protease responsible for the processing and secretion of IL-1β and IL-18, which are closely related to the induction of inflammation. However, limited evidence addresses the participation of caspase-1 in infla...

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Main Authors: Zamboni Dario S, Verri Waldiceu A, Sonego Fabiane, Guerrero Ana T, Souza Guilherme R, Vieira Silvio M, Pinto Larissa G, Talbot Jhimmy, Cunha Thiago M, Ferreira Sergio H, Cunha Fernando Q
Format: Article
Language:English
Published: SAGE Publishing 2010-10-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/6/1/63