Beta-Lactams Dosing in Critically Ill Patients with Gram-Negative Bacterial Infections: A PK/PD Approach

Beta-Lactams Dosing in Critically Ill Patients with Gram-Negative Bacterial Infections: A PK/PD Approach

Beta-lactam antibiotics are often the backbone of treatment for Gram-negative infections in the critically ill. Beta-lactams exhibit time-dependent killing, and their efficacy depends on the percentage of dosing interval that the concentration remains above the minimum inhibitory concentration. The...

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Bibliographic Details
Main Authors: Kelly L. Maguigan, Mohammad H. Al-Shaer, Charles A. Peloquin
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antibiotics
Subjects:
beta-lactams
PK/PD
critical care
resistance
Gram-negative
Online Access:https://www.mdpi.com/2079-6382/10/10/1154

Internet

https://www.mdpi.com/2079-6382/10/10/1154

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