The Effect of Hypothermic Machine Perfusion to Ameliorate Ischemia-Reperfusion Injury in Donor Organs

The Effect of Hypothermic Machine Perfusion to Ameliorate Ischemia-Reperfusion Injury in Donor Organs

Hypothermic machine perfusion (HMP) has become the new gold standard in clinical donor kidney preservation and a promising novel strategy in higher risk donor livers in several countries. As shown by meta-analysis for the kidney, HMP decreases the risk of delayed graft function (DGF) and improves gr...

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Bibliographic Details
Main Authors: Laura W. D. Knijff, Cees van Kooten, Rutger J. Ploeg
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
hypothermic machine perfusion
ischemia-reperfusion injury
HIF
cell death
endothelial dysfunction
immune response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.848352/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.848352/full

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