The α-mating factor secretion signals and endogenous signal peptides for recombinant protein secretion in Komagataella phaffii

Abstract Background The budding yeast Komagataella phaffii (Pichia pastoris) is widely employed to secrete proteins of academic and industrial interest. For secretory proteins, signal peptides are the sorting signal to direct proteins from cytosol to extracellular matrix, and their secretion efficie...

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Bibliographic Details
Main Authors: Chenwei Zou, Lingfang Lu, Shengyan Wang, Chenshan Zhang, Xuequn Chen, Yao Lin, Yide Huang
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
Online Access:https://doi.org/10.1186/s13068-022-02243-6