Emerging roles of BMP9 and BMP10 in hereditary hemorrhagic telangiectasia

Rendu-Osler-Weber syndrome, also known as hereditary hemorrhagic telangiectasia (HHT), is an autosomal dominant vascular disorder. Three genes are causally related to HHT: the ENG gene encoding endoglin, a co-receptor of the TGFß family (HHT1), the ACVRL1 gene encoding ALK1 (activin receptor-like ki...

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Bibliographic Details
Main Authors: Emmanuelle eTillet, Sabine eBailly
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00456/full