Serum glial fibrillary acidic protein and neurofilament light chain in patients with early treated phenylketonuria

Serum glial fibrillary acidic protein and neurofilament light chain in patients with early treated phenylketonuria

To pave the way for healthy aging in early treated phenylketonuria (ETPKU) patients, a better understanding of the neurological course in this population is needed, requiring easy accessible biomarkers to monitor neurological disease progression in large cohorts. The objective of this pilot study wa...

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Bibliographic Details
Main Authors: Amelie S. Lotz-Havla, Sabrina Katzdobler, Brigitte Nuscher, Katharina Weiß, Johannes Levin, Joachim Havla, Esther M. Maier
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Neurology
Subjects:
phenylketonuria (PKU)
glial fibrillary acidic protein (GFAP)
neurofilament light chain (NFL)
Simoa assay
biomarkers brain alterations
optical coherence tomography
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.1011470/full

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https://www.frontiersin.org/articles/10.3389/fneur.2022.1011470/full

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