Serum glial fibrillary acidic protein and neurofilament light chain in patients with early treated phenylketonuria

Serum glial fibrillary acidic protein and neurofilament light chain in patients with early treated phenylketonuria

To pave the way for healthy aging in early treated phenylketonuria (ETPKU) patients, a better understanding of the neurological course in this population is needed, requiring easy accessible biomarkers to monitor neurological disease progression in large cohorts. The objective of this pilot study wa...

Full description

Bibliographic Details
Main Authors:	Amelie S. Lotz-Havla, Sabrina Katzdobler, Brigitte Nuscher, Katharina Weiß, Johannes Levin, Joachim Havla, Esther M. Maier
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-09-01
Series:	Frontiers in Neurology
Subjects:	phenylketonuria (PKU) glial fibrillary acidic protein (GFAP) neurofilament light chain (NFL) Simoa assay biomarkers brain alterations optical coherence tomography
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2022.1011470/full

Similar Items

Serum and cerebrospinal fluid neurofilament light chain and glial fibrillary acid protein levels in early and advanced stages of cerebral amyloid Angiopathy
by: Ingeborg Rasing, et al.
Published: (2024-04-01)

Plasma glial fibrillary acidic protein and neurofilament light chain for the diagnostic and prognostic evaluation of frontotemporal dementia
by: Nuole Zhu, et al.
Published: (2021-12-01)

Glial Activation Markers in CSF and Serum From Patients With Primary Progressive Multiple Sclerosis: Potential of Serum GFAP as Disease Severity Marker?
by: Ahmed Abdelhak, et al.
Published: (2019-03-01)

Evaluation of serum neurofilament light chain and glial fibrillary acidic protein in the diagnosis of Alzheimer’s disease
by: Tangni Fang, et al.
Published: (2024-01-01)

Real-world applicability of glial fibrillary acidic protein and neurofilament light chain in Alzheimer’s disease
by: Tandis Parvizi, et al.
Published: (2022-08-01)

Plasma neurofilament light chain and glial fibrillary acidic protein predict stroke in CADASIL
by: Chih-Hao Chen, et al.
Published: (2020-04-01)

A case of glial fibrillary acidotic protein (GFAP) meningoencephalitis with rheumatoid arthritis
by: Mehri Salari, et al.
Published: (2023-03-01)

Parainfectious Anti-Glial Fibrillary Acidic Protein-Associated Meningoencephalitis
by: Jae Young Joo, et al.
Published: (2022-01-01)

Case report: Headache as the sole neurological symptom in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy
by: Eslam Shosha, et al.
Published: (2024-04-01)

Autoimmune glial fibrillary acidic protein astrocytopathy associated with breast cancer: a case report
by: Tomonori Yaguchi, et al.
Published: (2023-04-01)

Serum GFAP, NfL, and tau concentrations are associated with worse neurobehavioral functioning following mild, moderate, and severe TBI: a cross-sectional multiple-cohort study
by: Katie A. Edwards, et al.
Published: (2024-01-01)

Epidemiological aspects in phenylketonuria patients from a region in northwestern Romania
by: Alin Remus Iuhas, et al.
Published: (2022-06-01)

Whether Serum Glial Fibrillary Acidic Protein (GFAP) Can Be Used as a Diagnostic Biomarker in Patients With Glioblastoma?
by: Charandeep Singh Gandhoke, et al.
Published: (2020-01-01)

Phenylketonuria: A Comprehensive Review of Pathophysiology, Diagnosis, and Management Strategies
by: Agata Konopka, et al.
Published: (2024-08-01)

Glial Fibrillary Acidic Protein sebagai Penanda Prognostik pada Stroke Iskemik Akut
by: Lisda Amalia
Published: (2023-10-01)

Evaluating plasma biomarkers NfL, GFAP, GDF15, and FGF21 as indicators of disease severity in Charcot–Marie Tooth patients
by: Dace Pretkalnina, et al.
Published: (2025-01-01)

Magnetic Resonance Imaging Characteristics of Autoimmune Glial Fibrillary Acidic Protein (GFAP) Astrocytopathy: A Pediatric Series in Southwest China
by: Cheng W, et al.
Published: (2023-07-01)

Alzheimer’s Disease Biomarkers Revisited From the Amyloid Cascade Hypothesis Standpoint
by: Deborah O. T. Alawode, et al.
Published: (2022-04-01)

Genetic and clinical characteristics of patients with phenylketonuria in Slovenia
by: Urh Grošelj, et al.
Published: (2013-12-01)

Neurofilament light chain and glial fibrillary acid protein levels are elevated in post-mild COVID-19 or asymptomatic SARS-CoV-2 cases
by: Domenico Plantone, et al.
Published: (2024-03-01)

Serum glial fibrillary acidic protein indicates memory impairment in patients with chronic heart failure
by: Jan Traub, et al.
Published: (2022-08-01)

Incidence of Phenylketonuria in Southern Khorasan (2012- 2014): Short Communication
by: Zohre Saadatinasab, et al.
Published: (2015-10-01)

LEVELS OF GLIAL FIBRILLARY ACIDIC PROTEIN IN SERUM AFTER CEREBRAL ISCHEMIA IN THE NEONATAL PERIOD
by: D. V. Blinov
Published: (2016-06-01)

Clinical analysis and case series report on autoimmune glial fibrillary acidic protein astrocytopathy presenting with autonomic dysfunction
by: Xiao Ke Wu, et al.
Published: (2025-01-01)

Glial Fibrillary Acidic Protein in Blood as a Disease Biomarker of Neuromyelitis Optica Spectrum Disorders
by: Hyunjin Kim, et al.
Published: (2022-03-01)

Characteristics and outcomes of pregnancies among women with phenylketonuria from the NBS Connect registry
by: Aileen Kenneson, et al.
Published: (2024-06-01)

Impact of phenylalanine on cognitive, cerebral, and neurometabolic parameters in adult patients with phenylketonuria (the PICO study): a randomized, placebo-controlled, crossover, noninferiority trial
by: Roman Trepp, et al.
Published: (2020-02-01)

Clinical Features of Multicenter Autoimmune Glial Fibrillary Acidic Protein Astrocytosis
by: ZHENG Xiujun, et al.
Published: (2022-04-01)

Comparison of glial fibrillary acidic protein-immunoglobulin G-associated myelitis with myelin oligodendrocyte glycoprotein-immunoglobulin G-associated myelitis
by: Mengyang Sun, et al.
Published: (2023-10-01)

Glial Fibrillary Acidic Protein: A Biomarker and Drug Target for Alzheimer’s Disease
by: Akshatha Ganne, et al.
Published: (2022-06-01)

Cognitive profile in Egyptian multiple sclerosis patients has no correlation with serum neurofilament level
by: Amira Sayed, et al.
Published: (2024-06-01)

Association between neurofilament light chain concentration and lesion size in dogs with meningoencephalitis of unknown origin
by: Taesik Yun, et al.
Published: (2023-07-01)

Cross‐sectional and longitudinal evaluation of plasma glial fibrillary acidic protein to detect and predict clinical syndromes of Alzheimer's disease
by: Madeline Ally, et al.
Published: (2023-10-01)

Case report: Autoimmune glial fibrillary acidic protein astrocytopathy with overlapping autoimmune syndrome
by: Wu-xiao Wei, et al.
Published: (2024-10-01)

Citicoline affects serum angiostatin and neurospecific protein levels in patients with atrial fibrillation and ischemic stroke
by: A. A. Tykhomyrov, et al.
Published: (2019-10-01)

Autoimmune glial fibrillary acidic protein astrocytopathy misdiagnosed as intracranial infectious diseases: case reports and literature review
by: Runhua Bai, et al.
Published: (2025-01-01)

Phenylketonuria Patients’ and Their Caregivers’ Perception of the Pandemic Lockdown: The Results of a National Online Survey
by: Dariusz Walkowiak, et al.
Published: (2022-01-01)

Proteomic profiling of the brain from the <i>wobbler</i> mouse model of amyotrophic lateral sclerosis reveals elevated levels of the astrogliosis marker glial fibrillary acidic protein
by: Sandra Murphy, et al.
Published: (2023-08-01)

Professional activity, gender and disease-related emotions: The impact on parents' experiences in caring for children with phenylketonuria
by: Dariusz Walkowiak, et al.
Published: (2023-09-01)

Total choline intake and working memory performance in adults with phenylketonuria
by: Meriah S. Schoen, et al.
Published: (2023-07-01)