Creation of a cardiotropic adeno-associated virus: the story of viral directed evolution

<p>Abstract</p> <p>Adeno-associated virus (AAV) is an important vector system for human gene therapy. Although use of AAV serotypes can result in efficient myocardial gene transfer, improvements in the transduction efficiency and specificity are still required. As a method for arti...

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Bibliographic Details
Main Authors: Yang Lin, Xiao Xiao
Format: Article
Language:English
Published: BMC 2013-02-01
Series:Virology Journal
Subjects:
Online Access:http://www.virologyj.com/content/10/1/50