Disposition of Hexahydrocannabinol Epimers and Their Metabolites in Biological Matrices following a Single Administration of Smoked Hexahydrocannabinol: A Preliminary Study

Disposition of Hexahydrocannabinol Epimers and Their Metabolites in Biological Matrices following a Single Administration of Smoked Hexahydrocannabinol: A Preliminary Study

In 2023, hexahydrocannabinol (HHC) attracted the attention of international agencies due to its rapid spread in the illegal market. Although it was discovered in 1940, less is known about the pharmacology of its two naturally occurring epimers, 9(R)-HHC and 9(S)-HHC. Thus, we aimed to investigate th...

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Bibliographic Details
Main Authors: Annagiulia Di Trana, Alessandro Di Giorgi, Giorgia Sprega, Jeremy Carlier, Giorgi Kobidze, Eva Montanari, Omayema Taoussi, Giulia Bambagiotti, Maria Sofia Fede, Alfredo Fabrizio Lo Faro, Anastasio Tini, Francesco Paolo Busardò, Simona Pichini
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Pharmaceuticals
Subjects:
hexahydrocannabinol epimers
pharmacokinetics
HHC metabolites
biological matrices
Online Access:https://www.mdpi.com/1424-8247/17/2/249

Internet

https://www.mdpi.com/1424-8247/17/2/249

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