A 9-mRNA signature measured from whole blood by a prototype PCR panel predicts 28-day mortality upon admission of critically ill COVID-19 patients

A 9-mRNA signature measured from whole blood by a prototype PCR panel predicts 28-day mortality upon admission of critically ill COVID-19 patients

Immune responses affiliated with COVID-19 severity have been characterized and associated with deleterious outcomes. These approaches were mainly based on research tools not usable in routine clinical practice at the bedside. We observed that a multiplex transcriptomic panel prototype termed Immune...

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Bibliographic Details
Main Authors: Claire Tardiveau, Guillaume Monneret, Anne-Claire Lukaszewicz, Valérie Cheynet, Elisabeth Cerrato, Katia Imhoff, Estelle Peronnet, Maxime Bodinier, Louis Kreitmann, Sophie Blein, Jean-François Llitjos, Filippo Conti, Morgane Gossez, Marielle Buisson, Hodane Yonis, Martin Cour, Laurent Argaud, Marie-Charlotte Delignette, Florent Wallet, Frederic Dailler, Céline Monard, Karen Brengel-Pesce, Fabienne Venet, the RICO study group
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
transcriptomic multiplex tool
SARS-CoV-2 infection
immune response
28-day mortality prediction
personalized medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1022750/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1022750/full

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