Discovering Che-1/AATF: a new attractive target for cancer therapy

The transcriptional cofactor Che-1/AATF is currently emerging as an important component of the DNA damage response machinery, the complex signaling network that maintains genome integrity and prevents tumorigenesis. Moreover this protein is involved in a wide range of cellular pathways, regulating p...

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Bibliographic Details
Main Authors: Simona eIezzi, Maurizio eFanciulli
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00141/full