Molecular characterization of AIFM2/FSP1 inhibition by iFSP1-like molecules
Abstract Ferroptosis is a form of cell death characterized by phospholipid peroxidation, where numerous studies have suggested that the induction of ferroptosis is a therapeutic strategy to target therapy refractory cancer entities. Ferroptosis suppressor protein 1 (FSP1), an NAD(P)H-ubiquinone redu...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-04-01
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Series: | Cell Death and Disease |
Online Access: | https://doi.org/10.1038/s41419-023-05787-z |