Sauchinone alleviates dextran sulfate sodium-induced ulcerative colitis via NAD(P)H dehydrogenase [quinone] 1/NF-kB pathway and gut microbiota

Sauchinone alleviates dextran sulfate sodium-induced ulcerative colitis via NAD(P)H dehydrogenase [quinone] 1/NF-kB pathway and gut microbiota

ObjectiveThis study evaluated the effects of sauchinone on dextran sulfate sodium (DSS)-induced ulcerative colitis (UC) mice model and investigated the underlying mechanisms of the downstream pathway and gut microbiota.MethodsThe UC mice model was induced by DSS. The disease phenotypes were determin...

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Bibliographic Details
Main Authors: Kun Wu, Xianjun Liu, Xianglong Meng, Lingling Cao, Hao Li, Yingxin Bi, Mengyuan Wang, Mingchuan Wang, Yang Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Microbiology
Subjects:
sauchinone
ulcerative colitis
NF-kB pathway
NQO1
gut microbiota
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1084257/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1084257/full

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