Identification of platelet subpopulations in cryopreserved platelet components using multi-colour imaging flow cytometry

Abstract Cryopreservation of platelets, at  − 80 °C with 5–6% DMSO, results in externalisation of phosphatidylserine and the formation of extracellular vesicles (EVs), which may mediate their procoagulant function. The phenotypic features of procoagulant platelets overlap with other platelet subpopu...

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Bibliographic Details
Main Authors: Lacey Johnson, Pearl Lei, Lauren Waters, Matthew P. Padula, Denese C. Marks
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28352-2