Down-regulation of KLRB1 is associated with increased cell growth, metastasis, poor prognosis, as well as a dysfunctional immune microenvironment in LUAD

Down-regulation of KLRB1 is associated with increased cell growth, metastasis, poor prognosis, as well as a dysfunctional immune microenvironment in LUAD

Abstract Killer cell lectin-like receptor B1 (KLRB1) is implicated in cancer progression and immunity. In this study, we aimed to evaluate the expression levels of KLRB1 in lung adenocarcinoma (LUAD) and analyze the relationship between KLRB1 expression levels, LUAD progression, and the tumor immune...

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Bibliographic Details
Main Authors: Jiu-Ling Chen, Chuang-Yan Wu, Xiang-Yu Luo, Xue-Ying Wang, Fang-Ming Wang, Xin Huang, Wei Yuan, Qiang Guo
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Series:Scientific Reports
Subjects:
KLRB1
Lung adenocarcinoma
Prognosis
ROC
Disease-specific survival
Online Access:https://doi.org/10.1038/s41598-024-60414-x

Internet

https://doi.org/10.1038/s41598-024-60414-x

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