Sustained astrocytic clusterin expression improves remodeling after brain ischemia

Sustained astrocytic clusterin expression improves remodeling after brain ischemia

Clusterin is a glycoprotein highly expressed in response to tissue injury. Using clusterin-deficient (Clu−/−) mice, we investigated the role of clusterin after permanent middle cerebral artery occlusion (MCAO). In wild-type (WT) mice, clusterin mRNA displayed a sustained increase in the peri-infarct...

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Bibliographic Details
Main Authors: Anouk Imhof, Yves Charnay, Philippe G. Vallet, Bruce Aronow, Eniko Kovari, Lars E. French, Constantin Bouras, Panteleimon Giannakopoulos
Format: Article
Language:English
Published: Elsevier 2006-05-01
Series:Neurobiology of Disease
Subjects:
Astrocytes
Apolipoprotein J
Clusterin-deficient mice
Middle cerebral artery occlusion
Neuroprotective effect
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105003104

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http://www.sciencedirect.com/science/article/pii/S0969996105003104

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