Prothymosin α Plays Role as a Brain Guardian through Ecto-F<sub>1</sub> ATPase-P2Y<sub>12</sub> Complex and TLR4/MD2

Prothymosin alpha (ProTα) was discovered to be a necrosis inhibitor from the conditioned medium of a primary culture of rat cortical neurons under starved conditions. This protein carries out a neuronal cell-death-mode switch from necrosis to apoptosis, which is, in turn, suppressed by a variety of...

Full description

Bibliographic Details
Main Author: Hiroshi Ueda
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/12/3/496