Prothymosin α Plays Role as a Brain Guardian through Ecto-F<sub>1</sub> ATPase-P2Y<sub>12</sub> Complex and TLR4/MD2
Prothymosin alpha (ProTα) was discovered to be a necrosis inhibitor from the conditioned medium of a primary culture of rat cortical neurons under starved conditions. This protein carries out a neuronal cell-death-mode switch from necrosis to apoptosis, which is, in turn, suppressed by a variety of...
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Format: | Article |
Language: | English |
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MDPI AG
2023-02-01
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Series: | Cells |
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Online Access: | https://www.mdpi.com/2073-4409/12/3/496 |