Mast cells promote choroidal neovascularization in a model of age-related macular degeneration

Abstract ‘Wet’ age-related macular degeneration (AMD) is characterized by pathologic choroidal neovascularization (CNV) that destroys central vision. Abundant evidence points to inflammation and immune cell dysfunction in the progression of CNV in AMD. Mast cells are resident immune cells that contr...

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Bibliographic Details
Main Authors: Rabah Dabouz, Pénélope Abram, Jose Carlos Rivera, Sylvain Chemtob
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-024-03229-x