Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole.

Transcriptional differentiation of Trypanosoma brucei during in vitro acquisition of resistance to acoziborole.

Subspecies of the protozoan parasite Trypanosoma brucei are the causative agents of Human African Trypanosomiasis (HAT), a debilitating neglected tropical disease prevalent across sub-Saharan Africa. HAT case numbers have steadily decreased since the start of the century, and sustainable elimination...

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Bibliographic Details
Main Authors: Pieter C Steketee, Federica Giordani, Isabel M Vincent, Kathryn Crouch, Fiona Achcar, Nicholas J Dickens, Liam J Morrison, Annette MacLeod, Michael P Barrett
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009939

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https://doi.org/10.1371/journal.pntd.0009939

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