Targeting the NLRP3 Inflammasome as a New Therapeutic Option for Overcoming Cancer

Targeting the NLRP3 Inflammasome as a New Therapeutic Option for Overcoming Cancer

Inflammasomes are multiprotein complexes that regulate the maturation and secretion of the proinflammatory cytokines interleukin-1beta (IL-1β and interleukin-18 (IL-18) in response to various intracellular stimuli. As a member of the inflammasomes family, NLRP3 is the most studied and best character...

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Bibliographic Details
Main Authors: Sonia Missiroli, Mariasole Perrone, Caterina Boncompagni, Chiara Borghi, Alberto Campagnaro, Francesco Marchetti, Gabriele Anania, Pantaleo Greco, Francesco Fiorica, Paolo Pinton, Carlotta Giorgi
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Cancers
Subjects:
inflammation
NLRP3 inflammasome
inhibitors
target-therapy
Online Access:https://www.mdpi.com/2072-6694/13/10/2297

Internet

https://www.mdpi.com/2072-6694/13/10/2297

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