Prohormone convertase 2 activity is increased in the hippocampus of Wfs1 knockout mice

Prohormone convertase 2 activity is increased in the hippocampus of Wfs1 knockout mice

BackgroundMutations in WFS1 gene cause Wolfram syndrome, which is a rare autosomal recessive disorder, characterized by diabetes insipidus, diabetes mellitus, optic nerve atrophy and deafness (DIDMOAD). The WFS1 gene product wolframin is located in the endoplasmic reticulum. Mice lacking this gene e...

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Bibliographic Details
Main Authors: Karin eTein, Sergo eKasvandik, Sulev eKõks, Eero eVasar, Anton eTerasmaa
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Molecular Neuroscience
Subjects:
peptidomics
peptide processing
Mass-spectrometry
ProSAAS
7B2
WFS1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00045/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00045/full

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