Are Astrocytes the Predominant Cell Type for Activation of Nrf2 in Aging and Neurodegeneration?

Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor that regulates hundreds of antioxidant genes, and is activated in response to oxidative stress. Given that many neurodegenerative diseases including Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, H...

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Bibliographic Details
Main Author: Jeffrey R. Liddell
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/6/3/65