Development of Pleiotropic TrkB and 5-HT<sub>4</sub> Receptor Ligands as Neuroprotective Agents

Development of Pleiotropic TrkB and 5-HT<sub>4</sub> Receptor Ligands as Neuroprotective Agents

One common event that is the most detrimental in neurodegenerative disorders, even though they have a complex pathogenesis, is the increased rate of neuronal death. Endogenous neurotrophins consist of the major neuroprotective factors, while brain-derived neurotrophic factor (BDNF) and its high-affi...

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Bibliographic Details
Main Authors: Mirjana Antonijevic, Despoina Charou, Audrey Davis, Thomas Curel, Maria Valcarcel, Isbaal Ramos, Patricia Villacé, Sylvie Claeysen, Patrick Dallemagne, Achille Gravanis, Ioannis Charalampopoulos, Christophe Rochais
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Molecules
Subjects:
neurodegeneration
TrkB receptor
5-HT<sub>4</sub> receptor
neuronal survival
neurite differentiation
Online Access:https://www.mdpi.com/1420-3049/29/2/515

Internet

https://www.mdpi.com/1420-3049/29/2/515

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