Recombinant Envelope-Proteins with Mutations in the Conserved Fusion Loop Allow Specific Serological Diagnosis of Dengue-Infections.

Dengue virus (DENV) is a mosquito-borne flavivirus and a major international public health concern in many tropical and sub-tropical areas worldwide. DENV is divided into four major serotypes, and infection with one serotype leads to immunity against the same, but not the other serotypes. The specif...

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Bibliographic Details
Main Authors: Alexandra Rockstroh, Luisa Barzon, Monia Pacenti, Giorgio Palù, Matthias Niedrig, Sebastian Ulbert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-11-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4643925?pdf=render