Increased Sclerostin Levels after Further Ablation of Remnant Estrogen by Aromatase Inhibitors

Increased Sclerostin Levels after Further Ablation of Remnant Estrogen by Aromatase Inhibitors

BackgroundSclerostin is a secreted Wnt inhibitor produced almost exclusively by osteocytes, which inhibits bone formation. Aromatase inhibitors (AIs), which reduce the conversion of steroids to estrogen, are used to treat endocrine-responsive breast cancer. As AIs lower estrogen levels, they increas...

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Bibliographic Details
Main Authors: Wonjin Kim, Yoonjung Chung, Se Hwa Kim, Sehee Park, Jae Hyun Bae, Gyuri Kim, Su Jin Lee, Jo Eun Kim, Byeong-Woo Park, Sung-Kil Lim, Yumie Rhee
Format: Article
Language:English
Published: Korean Endocrine Society 2015-03-01
Series:Endocrinology and Metabolism
Subjects:
Sclerostin
Breast neoplasms
Aromatase inhibitors
Osteoporosis
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-30-58.pdf

Internet

http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-30-58.pdf

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