Targeting myeloid checkpoint Siglec-10 reactivates antitumor immunity and improves anti-programmed cell death 1 efficacy in gastric cancer

Targeting myeloid checkpoint Siglec-10 reactivates antitumor immunity and improves anti-programmed cell death 1 efficacy in gastric cancer

Objective Immunotherapy has not yielded satisfactory therapeutic responses in gastric cancer (GC). However, targeting myeloid checkpoints holds promise for expanding the potential of immunotherapy. This study aims to evaluate the critical role of Siglec-10+ tumor-associated macrophages (TAMs) in reg...

Full description

Bibliographic Details
Main Authors: Heng Zhang, Chao Lin, Hongyong He, Hao Liu, Ruochen Li, He Li, Jiejie Xu, Fei Shao, Yun Gu, Hanji Fang, Jieti Wang, Kunpeng Lv, Mengyao Sun
Format: Article
Language:English
Published: BMJ Publishing Group 2023-11-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/11/11/e007669.full

Internet

https://jitc.bmj.com/content/11/11/e007669.full

Similar Items