Pathogenicity of PKCγ Genetic Variants—Possible Function as a Non-Invasive Diagnostic Biomarker in Ovarian Cancer

Pathogenicity of PKCγ Genetic Variants—Possible Function as a Non-Invasive Diagnostic Biomarker in Ovarian Cancer

Ovarian cancer has the highest mortality rate among gynecologic malignancies, owing to its misdiagnosis or late diagnosis. Identification of its genetic determinants could improve disease outcomes. Conventional Protein Kinase C-γ (PKCγ) dysregulation is reported in several cancers. Similarly, its va...

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Bibliographic Details
Main Authors: Kanza Shahid, Khushbukhat Khan, Yasmin Badshah, Naeem Mahmood Ashraf, Arslan Hamid, Janeen H. Trembley, Maria Shabbir, Tayyaba Afsar, Ali Almajwal, Ali Abusharha, Suhail Razak
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Genes
Subjects:
protein kinase c-gamma (PKCγ)
ovarian cancer
protein-protein docking
molecular dynamics simulation
Online Access:https://www.mdpi.com/2073-4425/14/1/236

Internet

https://www.mdpi.com/2073-4425/14/1/236

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