SNPs in 3′UTR miRNA Target Sequences Associated with Individual Drug Susceptibility

SNPs in 3′UTR miRNA Target Sequences Associated with Individual Drug Susceptibility

The complementary interaction of microRNAs (miRNAs) with their binding sites in the 3′untranslated regions (3′UTRs) of target gene mRNAs represses translation, playing a leading role in gene expression control. MiRNA recognition elements (MREs) in the 3′UTRs of genes often contain single nucleotide...

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Bibliographic Details
Main Authors: Elena Rykova, Nikita Ershov, Igor Damarov, Tatiana Merkulova
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
microRNA (miRNA)
miRNA target sites
single nucleotide polymorphisms (SNPs)
3′untranslated regions (3′UTRs)
drug response
pharmacogenes
Online Access:https://www.mdpi.com/1422-0067/23/22/13725

Internet

https://www.mdpi.com/1422-0067/23/22/13725

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