Mechanisms and evolutionary patterns of mammalian and avian dosage compensation.

Mechanisms and evolutionary patterns of mammalian and avian dosage compensation.

As a result of sex chromosome differentiation from ancestral autosomes, male mammalian cells only contain one X chromosome. It has long been hypothesized that X-linked gene expression levels have become doubled in males to restore the original transcriptional output, and that the resulting X overexp...

Full description

Bibliographic Details
Main Authors: Philippe Julien, David Brawand, Magali Soumillon, Anamaria Necsulea, Angélica Liechti, Frédéric Schütz, Tasman Daish, Frank Grützner, Henrik Kaessmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22615540/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22615540/?tool=EBI

Similar Items