Inhibition of Sp1 functions by its sequestration into PML nuclear bodies.

Promyelocytic leukemia nuclear bodies (PML NBs) are comprised of PML and a striking variety of its associated proteins. Various cellular functions have been attributed to PML NBs, including the regulation of gene expression. We report here that induced expression of PML recruits Sp1 into PML NBs, le...

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Bibliographic Details
Main Authors: June Li, Wen-Xin Zou, Kun-Sang Chang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3984170?pdf=render