Elucidation of the Role of SMAD4 in Epithelial–Mesenchymal Plasticity: Does It Help to Better Understand the Consequences of <i>DPC4</i> Inactivation in the Malignant Progression of Pancreatic Ductal Adenocarcinoma?

Elucidation of the Role of SMAD4 in Epithelial–Mesenchymal Plasticity: Does It Help to Better Understand the Consequences of <i>DPC4</i> Inactivation in the Malignant Progression of Pancreatic Ductal Adenocarcinoma?

Pancreatic ductal adenocarcinoma (PDAC) is the 4th leading cause of cancer-related mortality worldwide, with a 5-year-survival rate below 10% that is the lowest of all cancer types [...]

Bibliographic Details
Main Authors: Hendrik Ungefroren, Björn Konukiewitz, Rüdiger Braun, Ulrich Friedrich Wellner, Tobias Keck, Jens-Uwe Marquardt
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
n/a
Online Access:https://www.mdpi.com/2072-6694/15/3/581

Internet

https://www.mdpi.com/2072-6694/15/3/581

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