Types and Mechanisms of Efflux Pump Systems and the Potential of Efflux Pump Inhibitors in the Restoration of Antimicrobial Susceptibility, with a Special Reference to <i>Acinetobacter baumannii</i>

Types and Mechanisms of Efflux Pump Systems and the Potential of Efflux Pump Inhibitors in the Restoration of Antimicrobial Susceptibility, with a Special Reference to <i>Acinetobacter baumannii</i>

Bacteria express a plethora of efflux pumps that can transport structurally varied molecules, including antimicrobial agents and antibiotics, out of cells. Thus, efflux pump systems participate in lowering intracellular concentrations of antibiotics, which allows phenotypic multidrug-resistant (MDR)...

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Bibliographic Details
Main Authors: Kira M. Zack, Trent Sorenson, Suresh G. Joshi
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Pathogens
Subjects:
<i>Acinetobacter baumannii</i>
antibiotics
carbapenem resistance
CRAB
efflux pump
efflux pump inhibitors
Online Access:https://www.mdpi.com/2076-0817/13/3/197

Internet

https://www.mdpi.com/2076-0817/13/3/197

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