Biological agents and the aging brain: glial inflammation and neurotoxic signaling

Neuroinflammation is a universal characteristic of brain aging and neurological disorders, irrespective of the disease state. Glial inflammation mediates this signaling, through astrocyte and microglial polarization from neuroprotective to neurotoxic phenotypes. Glial reactivity results in the loss...

Full description

Bibliographic Details
Main Authors: Amanda S. Latham, Julie A. Moreno, Charlize E. Geer
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Aging
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fragi.2023.1244149/full