Biological agents and the aging brain: glial inflammation and neurotoxic signaling
Neuroinflammation is a universal characteristic of brain aging and neurological disorders, irrespective of the disease state. Glial inflammation mediates this signaling, through astrocyte and microglial polarization from neuroprotective to neurotoxic phenotypes. Glial reactivity results in the loss...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-08-01
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Series: | Frontiers in Aging |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fragi.2023.1244149/full |