Exploring the tumor-suppressive role of miRNA-200c in head and neck squamous cell carcinoma: Potential and mechanisms of exosome-mediated delivery for therapeutic applications

Exploring the tumor-suppressive role of miRNA-200c in head and neck squamous cell carcinoma: Potential and mechanisms of exosome-mediated delivery for therapeutic applications

Head and neck squamous cell carcinoma (HNSCC) remains a challenging malignancy due to its high rates of recurrence, metastasis, and resistance to conventional therapies. microRNA-200c (miRNA-200c) has emerged as a critical tumor suppressor in HNSCC, with the potential to inhibit epithelial-mesenchym...

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Bibliographic Details
Main Authors: Mohamed S. Kishta, Aya Khamis, Hafez AM, Abdelrahman H. Elshaar, Désirée Gül
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Translational Oncology
Subjects:
Head and neck squamous cell carcinoma
microRNA
Epithelial-mesenchymal transition
Exosomes
Targeted therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324003437

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http://www.sciencedirect.com/science/article/pii/S1936523324003437

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