Development of a repeat-exposure penile SHIV infection model in macaques to evaluate biomedical preventions against HIV.

Development of a repeat-exposure penile SHIV infection model in macaques to evaluate biomedical preventions against HIV.

Penile acquisition of HIV infection contributes substantially to the global epidemic. Our goal was to establish a preclinical macaque model of penile HIV infection for evaluating the efficacy of new HIV prevention modalities. Rhesus macaques were challenged once or twice weekly with consistent doses...

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Bibliographic Details
Main Authors: David A Garber, James Mitchell, Debra Adams, Patricia Guenthner, Frank Deyounks, Shanon Ellis, Kristen Kelley, Ryan Johnson, Charles Dobard, Walid Heneine, Janet McNicholl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5870976?pdf=render

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http://europepmc.org/articles/PMC5870976?pdf=render

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