Schwann cell durotaxis can be guided by physiologically relevant stiffness gradients

Abstract Background Successful nerve regeneration depends upon directed migration of morphologically specialized repair state Schwann cells across a nerve defect. Although several groups have studied directed migration of Schwann cells in response to chemical or topographic cues, the current underst...

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Bibliographic Details
Main Authors: Elisabeth B. Evans, Samantha W. Brady, Anubhav Tripathi, Diane Hoffman-Kim
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2018-05-01
Series:Biomaterials Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40824-018-0124-z