Circ-CSNK1G1 promotes cell proliferation, migration, invasion and glycolysis metabolism during triple-negative breast cancer progression by modulating the miR-28-5p/LDHA pathway

Circ-CSNK1G1 promotes cell proliferation, migration, invasion and glycolysis metabolism during triple-negative breast cancer progression by modulating the miR-28-5p/LDHA pathway

Highlights 1. Circ-CSNK1G1 is upregulated in TNBC. 2. Circ-CSNK1G1 knockdown inhibits the proliferation, migration, invasion and glycolysis energy metabolism of TNBC cells. 3. Circ-CSNK1G1 knockdown inhibits tumor formation in vivo. 4. Circ-CSNK1G1 promotes TNBC development by regulating the miR-28-...

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Bibliographic Details
Main Authors: Xiaochen Zan, Wenfang Li, Geng Wang, Jie Yuan, Yongbiao Ai, Jun Huang, Zhi Li
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Reproductive Biology and Endocrinology
Subjects:
circ-CSNK1G1
Triple-negative breast cancer
miR-28-5p
LDHA
Online Access:https://doi.org/10.1186/s12958-022-00998-z

Internet

https://doi.org/10.1186/s12958-022-00998-z

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