Na<sup>+</sup>/K<sup>+</sup>-ATPase Revisited: On Its Mechanism of Action, Role in Cancer, and Activity Modulation

Na<sup>+</sup>/K<sup>+</sup>-ATPase Revisited: On Its Mechanism of Action, Role in Cancer, and Activity Modulation

Maintenance of Na<sup>+</sup> and K<sup>+</sup> gradients across the cell plasma membrane is an essential process for mammalian cell survival. An enzyme responsible for this process, sodium-potassium ATPase (NKA), has been currently extensively studied as a potential anticanc...

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Bibliographic Details
Main Authors: Jiří Bejček, Vojtěch Spiwok, Eva Kmoníčková, Silvie Rimpelová
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
anticancer activity
cardiac glycosides
combination therapy
digoxin
digitoxin
digitoxigenin
Online Access:https://www.mdpi.com/1420-3049/26/7/1905

Internet

https://www.mdpi.com/1420-3049/26/7/1905

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