Application of the Reuterin System as Food Preservative or Health-Promoting Agent: A Critical Review
The reuterin system is a complex multi-component antimicrobial system produced by <i>Limosilactobacillus reuteri</i> by metabolizing glycerol. The system mainly includes 3-hydroxypropionaldehyde (3-HPA, reuterin), 3-HPA dimer, 3-HPA hydrate, acrolein and 3-hydroxypropionic acid, and has...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/11/24/4000 |
| _version_ | 1797458751894061056 |
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| author | Mao-Cheng Sun Zi-Yi Hu Dian-Dian Li Yu-Xin Chen Jing-Hui Xi Chang-Hui Zhao |
| author_facet | Mao-Cheng Sun Zi-Yi Hu Dian-Dian Li Yu-Xin Chen Jing-Hui Xi Chang-Hui Zhao |
| author_sort | Mao-Cheng Sun |
| collection | DOAJ |
| description | The reuterin system is a complex multi-component antimicrobial system produced by <i>Limosilactobacillus reuteri</i> by metabolizing glycerol. The system mainly includes 3-hydroxypropionaldehyde (3-HPA, reuterin), 3-HPA dimer, 3-HPA hydrate, acrolein and 3-hydroxypropionic acid, and has great potential to be applied in the food and medical industries due to its functional versatility. It has been reported that the reuterin system possesses regulation of intestinal flora and anti-infection, anti-inflammatory and anti-cancer activities. Typically, the reuterin system exerts strong broad-spectrum antimicrobial properties. However, the antimicrobial mechanism of the reuterin system remains unclear, and its toxicity is still controversial. This paper presents an updated review on the biosynthesis, composition, biological production, antimicrobial mechanisms, stability, toxicity and potential applications of the reuterin system. Challenges and opportunities of the use of the reuterin system as a food preservative or health-promoting agent are also discussed. The present work will allow researchers to accelerate their studies toward solving critical challenges obstructing industrial applications of the reuterin system. |
| first_indexed | 2024-03-09T16:41:40Z |
| format | Article |
| id | doaj.art-008a2480e6344ec5b9e18704c7661afd |
| institution | Directory Open Access Journal |
| issn | 2304-8158 |
| language | English |
| last_indexed | 2024-03-09T16:41:40Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj.art-008a2480e6344ec5b9e18704c7661afd2023-11-24T14:50:38ZengMDPI AGFoods2304-81582022-12-011124400010.3390/foods11244000Application of the Reuterin System as Food Preservative or Health-Promoting Agent: A Critical ReviewMao-Cheng Sun0Zi-Yi Hu1Dian-Dian Li2Yu-Xin Chen3Jing-Hui Xi4Chang-Hui Zhao5College of Plant Science, Jilin University, Changchun 130062, ChinaInstitute of Biological and Medical Engineering, Guangdong Academy of Sciences, Guangzhou 510316, ChinaCollege of Food Science and Engineering, Changchun University, Changchun 130022, ChinaCollege of Food Science and Engineering, Changchun University, Changchun 130022, ChinaCollege of Plant Science, Jilin University, Changchun 130062, ChinaCollege of Food Science and Engineering, Jilin University, Changchun 130062, ChinaThe reuterin system is a complex multi-component antimicrobial system produced by <i>Limosilactobacillus reuteri</i> by metabolizing glycerol. The system mainly includes 3-hydroxypropionaldehyde (3-HPA, reuterin), 3-HPA dimer, 3-HPA hydrate, acrolein and 3-hydroxypropionic acid, and has great potential to be applied in the food and medical industries due to its functional versatility. It has been reported that the reuterin system possesses regulation of intestinal flora and anti-infection, anti-inflammatory and anti-cancer activities. Typically, the reuterin system exerts strong broad-spectrum antimicrobial properties. However, the antimicrobial mechanism of the reuterin system remains unclear, and its toxicity is still controversial. This paper presents an updated review on the biosynthesis, composition, biological production, antimicrobial mechanisms, stability, toxicity and potential applications of the reuterin system. Challenges and opportunities of the use of the reuterin system as a food preservative or health-promoting agent are also discussed. The present work will allow researchers to accelerate their studies toward solving critical challenges obstructing industrial applications of the reuterin system.https://www.mdpi.com/2304-8158/11/24/4000reuterinbiosynthesisantimicrobial mechanismtoxicitypreservative |
| spellingShingle | Mao-Cheng Sun Zi-Yi Hu Dian-Dian Li Yu-Xin Chen Jing-Hui Xi Chang-Hui Zhao Application of the Reuterin System as Food Preservative or Health-Promoting Agent: A Critical Review Foods reuterin biosynthesis antimicrobial mechanism toxicity preservative |
| title | Application of the Reuterin System as Food Preservative or Health-Promoting Agent: A Critical Review |
| title_full | Application of the Reuterin System as Food Preservative or Health-Promoting Agent: A Critical Review |
| title_fullStr | Application of the Reuterin System as Food Preservative or Health-Promoting Agent: A Critical Review |
| title_full_unstemmed | Application of the Reuterin System as Food Preservative or Health-Promoting Agent: A Critical Review |
| title_short | Application of the Reuterin System as Food Preservative or Health-Promoting Agent: A Critical Review |
| title_sort | application of the reuterin system as food preservative or health promoting agent a critical review |
| topic | reuterin biosynthesis antimicrobial mechanism toxicity preservative |
| url | https://www.mdpi.com/2304-8158/11/24/4000 |
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