Development of a bispecific nanobody conjugate broadly neutralizes diverse SARS-CoV-2 variants and structural basis for its broad neutralization.

Development of a bispecific nanobody conjugate broadly neutralizes diverse SARS-CoV-2 variants and structural basis for its broad neutralization.

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The continuous emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with increased transmissibility and profound immune-escape capacity makes it an urgent need to develop broad-spectrum therapeutics. Nanobodies have recently attracted extensive attentions due to their e...

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Bibliographic Details
Main Authors: Jing Yang, Sheng Lin, Zimin Chen, Fanli Yang, Liyan Guo, Lingling Wang, Yanping Duan, Xindan Zhang, Yushan Dai, Keqing Yin, Chongzhang Yu, Xin Yuan, Honglu Sun, Bin He, Yu Cao, Haoyu Ye, Haohao Dong, Xianbo Liu, Bo Chen, Jian Li, Qi Zhao, Guangwen Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-11-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011804&type=printable

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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011804&type=printable

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