Modelling the effect of subcellular mutations on the migration of cells in the colorectal crypt
Abstract Background Many cancers arise from mutations in cells within epithelial tissues. Mutations manifesting at the subcellular level influence the structure and function of the tissue resulting in cancer. Previous work has proposed how cell level properties can lead to mutant cell invasion, but...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-03-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-020-3391-3 |