The role of proteasome activators PA28αβ and PA200 in brown adipocyte differentiation and function

The role of proteasome activators PA28αβ and PA200 in brown adipocyte differentiation and function

IntroductionBrown adipocytes produce heat through non shivering thermogenesis (NST). To adapt to temperature cues, they possess a remarkably dynamic metabolism and undergo substantial cellular remodeling. The proteasome plays a central role in proteostasis and adaptive proteasome activity is require...

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Bibliographic Details
Main Authors: Zeynep Koçberber, Nienke Willemsen, Alexander Bartelt
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Endocrinology
Subjects:
BAT
brown adipocytes
proteostasis
ubiquitin-proteasome-system
PA28αβ
PA200
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1176733/full

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https://www.frontiersin.org/articles/10.3389/fendo.2023.1176733/full

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