Functional modifications of acid-sensing ion channels by ligand-gated chloride channels.

Functional modifications of acid-sensing ion channels by ligand-gated chloride channels.

Together, acid-sensing ion channels (ASICs) and epithelial sodium channels (ENaC) constitute the majority of voltage-independent sodium channels in mammals. ENaC is regulated by a chloride channel, the cystic fibrosis transmembrane conductance regulator (CFTR). Here we show that ASICs were reversibl...

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Bibliographic Details
Main Authors: Xuanmao Chen, Paul Whissell, Beverley A Orser, John F MacDonald
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3138761?pdf=render

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http://europepmc.org/articles/PMC3138761?pdf=render

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