Nanoparticle-based targeting of microglia improves the neural regeneration enhancing effects of immunosuppression in the zebrafish retina

Abstract Retinal Müller glia function as injury-induced stem-like cells in zebrafish but not mammals. However, insights gleaned from zebrafish have been applied to stimulate nascent regenerative responses in the mammalian retina. For instance, microglia/macrophages regulate Müller glia stem cell act...

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Bibliographic Details
Main Authors: Kevin Emmerich, David T. White, Siva P. Kambhampati, Grace L. Casado, Tian-Ming Fu, Zeeshaan Chunawala, Arpan Sahoo, Saumya Nimmagadda, Nimisha Krishnan, Meera T. Saxena, Steven L. Walker, Eric Betzig, Rangaramanujam M. Kannan, Jeff S. Mumm
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-04898-9