ZNF521 promotes acute myeloid leukemogenesis by suppressing the expression and acetylation of SMC3

Zinc finger protein 521 (ZNF521) participates in the self-renewal of hematopoietic stem cells, and its abnormal expression has been implicated to promote leukemia. However, the specific role of ZNF521 in leukemia has not been fully understood. In this study, we aimed to further elucidate its role. U...

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Bibliographic Details
Main Authors: Rong Qin, Tongshuo Yang, Hongchao Jiang, Ming Yu
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024135591