Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain

Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain

Summary: The epidermal growth factor receptor (EGFR) plays a role in cell proliferation and differentiation during healthy development and tumor growth; however, its requirement for brain development remains unclear. Here we used a conditional mouse allele for Egfr to examine its contributions to pe...

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Bibliographic Details
Main Authors: Xuying Zhang, Guanxi Xiao, Caroline Johnson, Yuheng Cai, Zachary K. Horowitz, Christine Mennicke, Robert Coffey, Mansoor Haider, David Threadgill, Rebecca Eliscu, Michael C. Oldham, Alon Greenbaum, H. Troy Ghashghaei
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:iScience
Subjects:
Neuroscience
Developmental neuroscience
Omics
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422300319X

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http://www.sciencedirect.com/science/article/pii/S258900422300319X

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